{"id":3784,"date":"2026-09-28T17:02:06","date_gmt":"2026-09-28T15:02:06","guid":{"rendered":"https:\/\/canalregionaltv.md\/?p=3784"},"modified":"2026-09-28T17:02:06","modified_gmt":"2026-09-28T15:02:06","slug":"ochii-ar-putea-indica-ritmul-imbatranirii-organismului-ce-au-descoperit-cercetatorii","status":"publish","type":"post","link":"https:\/\/canalregionaltv.md\/?p=3784","title":{"rendered":"Ochii ar putea indica ritmul \u00eemb\u0103tr\u00e2nirii organismului. Ce au descoperit cercet\u0103torii"},"content":{"rendered":"

O simpl\u0103 scanare a fundului de ochi ar putea oferi, \u00een viitor, informa\u021bii despre modul \u00een care \u00eemb\u0103tr\u00e2ne\u0219te organismul. La aceast\u0103 concluzie au ajuns cercet\u0103torii de la Universitatea Na\u021bional\u0103 din Seul, care au analizat aproape 30.000 de imagini ale retinei provenite de la peste 7.500 de persoane.<\/h3>\n

Studiul, publicat \u00een revista GeroScience<\/em>, analizeaz\u0103 posibilitatea folosirii imaginilor retiniene pentru estimarea v\u00e2rstei unei persoane \u0219i pentru identificarea unor diferen\u021be asociate procesului de \u00eemb\u0103tr\u00e2nire biologic\u0103, transmite digi24.ro<\/a>.<\/p>\n

Spre deosebire de v\u00e2rsta cronologic\u0103, stabilit\u0103 \u00een func\u021bie de data na\u0219terii, v\u00e2rsta biologic\u0103 \u00eencearc\u0103 s\u0103 arate c\u00e2t de mult este afectat organismul de procesul de \u00eemb\u0103tr\u00e2nire. Aceasta poate varia considerabil \u00eentre persoane de aceea\u0219i v\u00e2rst\u0103, \u00een func\u021bie de factori genetici, stil de via\u021b\u0103 \u0219i starea de s\u0103n\u0103tate.<\/p>\n

Ce poate \u201espune\u201d retina despre organism<\/h3>\n

Cercet\u0103torii s-au concentrat asupra metodei numite RAG \u2013 Retinal Age Gap, adic\u0103 diferen\u021ba dintre v\u00e2rsta estimat\u0103 pe baza retinei \u0219i v\u00e2rsta cronologic\u0103.<\/p>\n

Metoda folose\u0219te modele de inteligen\u021b\u0103 artificial\u0103 antrenate cu numeroase imagini ale retinei. Oamenii de \u0219tiin\u021b\u0103 sunt interesa\u021bi de aceast\u0103 zon\u0103 a ochiului deoarece retina este o extensie a sistemului nervos \u0219i con\u021bine o re\u021bea de vase de s\u00e2nge care poate reflecta anumite modific\u0103ri din organism.<\/p>\n

Pentru noul studiu, echipa de cercet\u0103tori a folosit 29.530 de scan\u0103ri retiniene de la 7.535 de participan\u021bi. Modelul a fost ulterior testat pe alte 14.832 de imagini provenite de la 7.416 persoane.<\/p>\n

Rezultatele au ar\u0103tat c\u0103 sistemul putea estima v\u00e2rsta cronologic\u0103 cu o eroare medie de aproximativ 2,5-2,7 ani.<\/p>\n

Cercet\u0103torii au analizat \u00eens\u0103 nu doar precizia algoritmului, ci \u0219i dac\u0103 diferen\u021ba dintre v\u00e2rsta estimat\u0103 a retinei \u0219i v\u00e2rsta real\u0103 era asociat\u0103 cu anumite probleme de s\u0103n\u0103tate sau obiceiuri.<\/p>\n

Diabetul, fumatul \u0219i cataracta, printre factorii asocia\u021bi<\/h3>\n

O valoare mai mare a RAG a fost asociat\u0103 cu mai multe afec\u021biuni \u0219i factori lega\u021bi de stilul de via\u021b\u0103.<\/p>\n

\u00cen cazul persoanelor cu diabet, diferen\u021ba asociat\u0103 a fost de aproximativ 2,52 ani. Pentru fum\u0103torii actuali, asocierea a fost de aproximativ 0,5 ani, iar pentru fo\u0219tii fum\u0103tori, de circa 0,46 ani.<\/p>\n

Degenerescen\u021ba macular\u0103 a fost asociat\u0103 cu o diferen\u021b\u0103 de aproximativ 0,6 ani, \u00een timp ce \u00een cazul cataractei diferen\u021ba a fost de aproximativ 1,86 ani.<\/p>\n

Cercet\u0103torii subliniaz\u0103 \u00eens\u0103 c\u0103 aceste valori nu trebuie interpretate ca o m\u0103surare direct\u0103 a v\u00e2rstei biologice. De exemplu, cataracta poate face ca imaginile retinei s\u0103 fie mai neclare, iar acest lucru poate influen\u021ba rezultatul algoritmului.<\/p>\n

Prin urmare, faptul c\u0103 modelul estimeaz\u0103 o retin\u0103 ca fiind \u201emai \u00een v\u00e2rst\u0103\u201d nu \u00eenseamn\u0103 automat c\u0103 organismul persoanei respective a \u00eemb\u0103tr\u00e2nit cu acela\u0219i num\u0103r de ani.<\/p>\n

Metoda nu poate fi folosit\u0103 \u00eenc\u0103 pentru evaluarea individual\u0103<\/h3>\n

Una dintre limitele importante ale cercet\u0103rii este c\u0103 metoda RAG nu a fost comparat\u0103 direct cu al\u021bi biomarkeri consacra\u021bi ai \u00eemb\u0103tr\u00e2nirii biologice.<\/p>\n

Autorii studiului consider\u0103 c\u0103 imaginile retinei con\u021bin informa\u021bii relevante despre v\u00e2rst\u0103, s\u0103n\u0103tatea ocular\u0103 \u0219i anumite caracteristici ale st\u0103rii generale de s\u0103n\u0103tate. Totu\u0219i, rezultatele actuale nu demonstreaz\u0103 c\u0103 RAG reprezint\u0103 o m\u0103sur\u0103 definitiv\u0103 a v\u00e2rstei biologice.<\/p>\n

\u201eRAG, o valoare rezidual\u0103 de predic\u021bie a v\u00e2rstei derivat\u0103 din imagistic\u0103, este, prin urmare, asociat\u0103 cu stilul de via\u021b\u0103, starea de s\u0103n\u0103tate sistemic\u0103 \u0219i cea ocular\u0103\u201d, noteaz\u0103 cercet\u0103torii.<\/p>\n

O alt\u0103 direc\u021bie analizat\u0103 a fost influen\u021ba sexului asupra rezultatelor. Cercet\u0103torii au folosit o metod\u0103 de \u201e\u00eenv\u0103\u021bare multitasking\u201d, prin care modelul estimeaz\u0103 simultan v\u00e2rsta \u0219i sexul, pentru a \u021bine cont de diferen\u021bele dintre b\u0103rba\u021bi \u0219i femei \u0219i pentru a reduce anumite surse de eroare.<\/p>\n

Scanarea retinei ar putea avea \u0219i alte utiliz\u0103ri<\/h3>\n

Oamenii de \u0219tiin\u021b\u0103 consider\u0103 c\u0103 tehnologia ar putea avea, \u00een viitor, aplica\u021bii care dep\u0103\u0219esc simpla estimare a v\u00e2rstei.<\/p>\n

\u00cen clinicile oftalmologice, unde examinarea fundului de ochi este deja utilizat\u0103, analiza RAG ar putea contribui la identificarea persoanelor care necesit\u0103 investiga\u021bii medicale suplimentare.<\/p>\n

\u201e\u00cen clinicile de oftalmologie unde se efectueaz\u0103 \u00een mod curent imagistica fundului de ochi, RAG poate ajuta la identificarea pacien\u021bilor care necesit\u0103 o evaluare sistemic\u0103 suplimentar\u0103\u201d, sus\u021bin autorii.<\/p>\n

Pentru moment, \u00eens\u0103, aceast\u0103 posibilitate r\u0103m\u00e2ne la nivel de cercetare. Sunt necesare studii suplimentare pentru a vedea dac\u0103 metoda poate fi utilizat\u0103 \u00een practica medical\u0103.<\/p>\n

Urm\u0103torul pas: monitorizarea acelora\u0219i persoane \u00een timp<\/h3>\n

Cercet\u0103torii spun c\u0103 este important ca participan\u021bii s\u0103 fie urm\u0103ri\u021bi pe perioade mai lungi. Astfel, oamenii de \u0219tiin\u021b\u0103 vor putea verifica dac\u0103 scorul RAG se modific\u0103 odat\u0103 cu \u00eenaintarea \u00een v\u00e2rst\u0103 \u0219i dac\u0103 schimb\u0103rile pot fi asociate cu tratamente sau modific\u0103ri ale stilului de via\u021b\u0103.<\/p>\n

De asemenea, metoda trebuie comparat\u0103 cu biomarkerii deja utiliza\u021bi pentru evaluarea \u00eemb\u0103tr\u00e2nirii biologice.<\/p>\n

\u201ePentru a stabili dac\u0103 acesta reflect\u0103 \u00eemb\u0103tr\u00e2nirea biologic\u0103, este necesar\u0103 o validare longitudinal\u0103 \u00een raport cu biomarkerii de \u00eemb\u0103tr\u00e2nire consacra\u021bi\u201d, precizeaz\u0103 cercet\u0103torii.<\/p>\n

Astfel, de\u0219i rezultatele indic\u0103 faptul c\u0103 retina poate con\u021bine informa\u021bii relevante despre procesul de \u00eemb\u0103tr\u00e2nire, o scanare a ochilor nu poate spune \u00een prezent cu exactitate c\u00e2t de repede \u00eemb\u0103tr\u00e2ne\u0219te organismul unei persoane. Autorii consider\u0103 c\u0103 RAG este, deocamdat\u0103, mai util pentru identificarea unor tendin\u021be la nivelul popula\u021biei dec\u00e2t pentru evaluarea riscului individual.<\/p>\n

Articolul Ochii ar putea indica ritmul \u00eemb\u0103tr\u00e2nirii organismului. Ce au descoperit cercet\u0103torii<\/a> apare prima dat\u0103 \u00een NordNews<\/a>.<\/p>","protected":false},"excerpt":{"rendered":"

O simpl\u0103 scanare a fundului de ochi ar putea oferi, \u00een viitor, informa\u021bii despre modul \u00een care \u00eemb\u0103tr\u00e2ne\u0219te organismul. La aceast\u0103 concluzie au ajuns cercet\u0103torii […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"class_list":["post-3784","post","type-post","status-publish","format-standard","hentry","category-uncategorized"],"yoast_head":"\nOchii ar putea indica ritmul \u00eemb\u0103tr\u00e2nirii organismului. 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